Development of new selective estrogen receptor modulators
AssigneesThe Regents of the University of California, Oregon Health & Science University
InventorsThomas S. Scanlan, Martin J. Kelly, Jian Qiu, Sandra Tobias, Oline K. Ronnekleiv
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Abstract
The present disclosure concerns a new class of selective estrogen receptor modulators (SERMs). The disclosure also includes the identification of a previously unknown membrane associated estrogen receptor. Methods for making and using the disclosed SERMs are disclosed, including pharmaceutical formulations of the disclosed novel compounds in useful compositions.
Claims4
A method for treating a condition associated with estrogen insufficiency in a subject, the condition comprising a disorder of temperature regulation, the method comprising administering to the subject an effective amount of a compound according to formula I:
Dependencies are inferred from the claim text.