Polyphenol compounds with modulating neurotransmitter release
AssigneeSungkyunkwan University Foundation for Corporate Collaboration
InventorsDae-Hyuk Kweon, Yeon-Kyun Shin, Chang-Hwa Jung, Yoo-Soo Yang
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Abstract
Disclosed is a composition for modulating the release of a neurotransmitter, which includes naturally extracted polyphenols as an active ingredient. The disclosed composition suppresses the formation of a SNARE complex, thereby modulating the release of a neurotransmitter, and thus can be used as a modulator for a reaction within a cell related to the SNARE complex. Such an inhibitor of the SNARE complex formation can be used as a composition for reducing wrinkles and relieving pain.
Claims3
A method for reducing skin-wrinkles by inhibiting formation of a SNARE complex and by modulating release of a neurotransmitter, the method comprising administering to a subject in need thereof a composition comprising at least one polyphenol compound selected from the group consisting of kaempferol, quercetin, myricetin, luteolin, delphinidin, cyanidin, butein, and ellagic acid, as an active ingredient.
Dependencies are inferred from the claim text.