Pyridyl- and pyrimidinyl-substituted pyrrole-, thiophene- and furane-derivatives as kinase inhibitors

A compound of the formula (I):

• wherein
• G is CH or nitrogen atom;
• W is an oxygen atom, NR1 or S(O)n;
• n is 0, 1 or 2;
• R1 and R3 independently represent hydrogen atom or an optionally substituted group selected from alkyl, cycloalkyl, alkenyl, alkynyl, heterocyclyl, heterocyclylalkyl, aryl, arylalkyl, heterocyclyloxy-alkyl and alkoxycarbonyl group;
• R2 is hydrogen or halogen atom, or an optionally substituted group selected from aryl, cycloalkyl and heterocyclyl group;
• R4 is hydrogen or halogen atom, or an optionally substituted alkyl or alkenyl group;
• R5 is hydrogen or halogen atom;
• R6 is hydrogen atom or NHR7;
• R7 is hydrogen atom, an optionally substituted group selected from alkyl, aryl, cycloalkyl and heterocyclyl group or —COR1 wherein R1 is as defined above;
• or a pharmaceutically acceptable salt thereof, with the proviso that the following compounds are excluded:
• 2,5-di(pyridin-4-yl)-thiophene-3-carboxylic acid amide,
• 2,5-di(pyridin-4-yl)-thiophene-3-carboxylic acid methylamide,
• 2,5-di(pyridin-4-yl)-4-methyl-pyrrole-3-carboxylic acid amide,
• 5-pyridin-4-yl-furan-3-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide,
• 5-pyridin-4-yl-furan-3-carboxylic acid (1-methyl-1,2,3,4-tetrahydro-quinolin-7-yl)-amide and
• N-[2-amino-1-(2,4-dichlorobenzyl)ethyl]-5-[2-(methylamino)pyrimidin-4-yl]thiophene-3-carboxamide.