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US 8,263,593 B2Granted
Therapeutic compounds
AssigneeAllergan, Inc.
InventorsYariv Donde, Jeremiah H. Nguyen
Life of this patent
Estimating the term…
Abstract
Compounds comprising formula (I) or a pharmaceutically acceptable salt thereof, are disclosed, wherein J, B, Y, and A are as described. Methods, compositions, and medicaments related thereto are also disclosed, for treating baldness, glaucoma or inflammatory bowel diseases.
Claims13
A compound having a structure
- or a pharmaceutically acceptable salt thereof, or a prodrug thereof;
- wherein Y is
- A is —(CH2)6—, cis —CH2CH═CH—(CH2)3—, or —CH2C≡C—(CH2)3—, wherein 1 or 2 carbon atoms may be replaced by S or O;
- or A is —(CH2)m—Ar—(CH2)o— wherein Ar is interarylene or heterointerarylene, the sum of m and o is 1, 2, 3, or 4, and wherein one CH2 may be replaced by S or O;
- J is C═O, CHOH, CHF, CHCl, CHBr, CF2, CCl2, CBr2, or CHCN;
- and
- B is substituted aryl or substituted heteroaryl.
4 more elements
Dependencies are inferred from the claim text.