Nanoemulsion comprising metabolites of ginseng saponin as an active component and a method for preparing the same, and a skin-care composition for anti-aging containing the same

A method of promoting fibroblast proliferation and collagen biosynthesis of the skin in a subject in need thereof, comprising topically applying to the subject's skin a skin-care composition containing a nanoemulsion that comprises metabolites of ginseng saponin as an effective component in an amount of 0.001%-50% by weight based on the total weight of the nanoemulsion composition, wherein said metabolites of ginseng saponin are extracted and purified from red ginseng, and wherein said metabolites of ginseng saponin are an admixture of

• 30-50 wt % 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol represented by the following formula 1
• wherein, R1 is O-Glc, R is OH and R3 is H;
• 5-25 wt % 20-O-β-D-glucopyranosyl-20(S)-protopanaxatriol represented by the following formula 2
• wherein, R1 is O-Glc, R2 is OH and R3 is OH;
• and
• 5-25 wt % 20-O-[α-L-arabinopyranosyl(1→6)-β-D-glucopyranosyl]-20(S)-protopanaxadiol represented by the following formula 3
• wherein R1 is O-Glc6-1Arap, R2 is OH and R3 is H.