HPV 16 peptide vaccine for head and neck cancer
AssigneesUniversity of Maryland, Baltimore, Mayo Foundation for Medical Education and Research
InventorsScott E. Strome, Esteban Celis
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Abstract
The present invention relates to Trojan antigens, and immunogenic compositions comprising the Trojan antigens. The present invention also relates to methods of generating an immune response in a subject using the Trojan antigens or immunogenic compositions. The present invention further relates to methods of treating squamous cell carcinoma of the head and neck (SCCHN) using the Trojan antigens and immunogenic compositions of the present invention.
Claims15
A isolated polypeptide comprising amino acids 1-43 of SEQ ID NO:
- 22.
A method of generating an immune response in a subject comprising administering a polypeptide comprising amino acids 1-43 of SEQ ID NO:
- 22, to a subject in an amount sufficient to induce an immune response in said subject.
A method of treating squamous cell carcinoma of the head and neck (SCCHN) comprising administering to a subject in need of such treatment a therapeutically-effective amount of a polypeptide comprising amino acids 1-43 of SEQ ID NO:
- 22.
Dependencies are inferred from the claim text.