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US 8,263,400 B2Granted
Method for expanding adult stem cells from blood and compositions and methods for using the same
AssigneeThankstem Srl
InventorsAlessandra Gambacurta, Marco Polettini
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Abstract
A method for the expansion of adult stem cells from blood, particularly but not only peripheral blood, involves removing adult stem cells from blood of a mammal, immediately expanding the stem cells via in-vitro treatment with MCSF (Macrophage Colony Stimulating Factor) at a concentration of about 8-15 nM, and purifying the expanded stem cells. Compositions and methods of using the expanded adult stem cells are also described.
Claims12
A method for expanding adult stem cells from blood comprising:
- a) obtaining a sample of blood of an adult mammal;
- b) immediately after the sample of blood has been taken from the mammal, treating the sample of blood in vitro with MCSF (macrophage colony stimulating factor) at a concentration of about 8-15 nM MCSF to obtain expanded stem cells in the sample of blood;
- and
- c) purifying the expanded stem cells.
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Dependencies are inferred from the claim text.