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US 8,263,386 B2Granted
Digital bio disc (DBD), DBD driver apparatus, and assay method using the same
AssigneeSamsung Electronics Co., Ltd.
InventorJae Chern Yoo
Life of this patent
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Abstract
An aspect of embodiment relates to a digital bio disc (DBD) including new valve control means and fluid movement system, a digital bio disc (DBD) driver apparatus, and an assay method using the same. More particularly, an aspect of embodiment relates to a DBD with a lab-on-a-chip for various diagnostic assays, nucleic acid hybridization assays, or immunoassays, a DBD driver apparatus integrated with a controller for controlling the DBD and a general optical disc (CD or DVD), and an assay method using the same.
Claims88
A digital bio-disc (DBD) comprising:
- a rotatable disk having a rotation axis, where the rotatable disk comprises:
- a sample inlet;
- chambers which reserve a buffer solution or a reaction solution, a nitrocellulose membrane where bio materials are arrayed, air holes disposed at both sides of the nitrocellulose membrane to dry the nitrocellulose membrane, hydrophobic channels through which fluid can flow between the sample inlet, and the chambers by centrifugal force, a hydrophilic channel formed between the chamber connected to the nitrocellulose membrane, and valve holes formed in a direction parallel to the rotation axis;
- a cylindrical permanent magnet placed on the valve holes, wherein the cylindrical permanent magnet is capable of opening and closing the valve hole by moving upward or downward in a direction parallel to the rotation axis;
- a plurality of non-movable permanent magnets closing the valve holes, wherein the non-movable permanent magnets are fixed above each of the valve holes;
- and a single movable permanent magnet capable of selective opening one of the valve holes, wherein the valve hole is opened only when the single movable permanent magnet is vertically aligned to the non-movable magnet, wherein the single movable permanent magnet is mounted on a radially movable slider disposed under the DBD.
3 more elements
Dependencies are inferred from the claim text.