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US 8,263,352 B2Granted
Diagnostic method for diseases by screening for hepcidin in human or animal tissues, blood or body fluids and therapeutic uses therefor
AssigneeDRG International, Inc.
InventorsHasan Kulaksiz, Cyril E. Geacintov, Alfred Jentzko, Wolfgang Stremmel
Life of this patent
Estimating the term…
Abstract
The present invention concerns a method of detecting hepcidin, prohepcidin or fragments thereof, by contacting the sample with an antibody or fragment thereof that specifically binds to one or more epitopes contained within amino acids 28-47 of SEQ ID NO:2.
Claims3
A method of detecting hepcidin comprising the steps of:
- (a) obtaining a tissue or fluid sample from a subject;
- and (b) contacting the sample with an antibody or fragment thereof that specifically binds to one or more epitopes contained within amino acids 28 to 47 of hepcidin of SEQ ID NO:2;
- wherein the tissue or fluid sample is selected from the group consisting of a kidney sample, a liver sample, and a urine sample, and wherein the method of detecting hepcidin is selected from the group consisting of Western blot, immunodot, immunohistochemistry, and immunofluorescence.
Dependencies are inferred from the claim text.