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US 8,263,351 B2Granted
Diagnostic methods for congestive heart failure
AssigneeNexus Dx, Inc.
InventorsGeorge Jackowski, Tracy Van Lieshout, Brad Thatcher, Rulin Zhang, Jason Yantha, Michele Rasamoelisolo
Life of this patent
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Abstract
The invention provides an assay for the quantification of circulating glycophorin in biological fluid samples. The circulating glycophorin measured by this assay is a truncated glycophorin diagnostic for congestive heart failure (CHF).
Claims7
A method for determining whether a subject is suffering from congestive heart failure comprising:
- analyzing a body fluid of the subject to detect a presence and concentration level of unbound and freely circulating truncated glycophorin in said body fluid,
- correlating an elevated level of said truncated glycophorin with congestive heart failure.
A method for determining whether a subject is suffering from congestive heart failure comprising:
- analyzing a body fluid of the subject to detect a presence and concentration level of an unbound and freely circulating truncated glycophorin recognized by monoclonal antibody 3F4(ATCC PTA-5154);
- and
- correlating an elevated level of said truncated glycophorin with congestive heart failure.
Dependencies are inferred from the claim text.