Abnormal prion protein binder, and method for detection of abnormal prion protein
AssigneeMorinaga Milk Industry Co., Ltd.
InventorsYoshifumi Iwamaru, Tetsuya Kuhara
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Abstract
Disclosed are: a method for detecting pathogenic isoform of prion protein as distinguished from normal prion protein in a simple manner, rapidly, with a high degree of sensitivity and quantitatively without the need of the enzymatic treatment with protease K; and a reagent for use in the method. Specifically disclosed are: a pathogenic isoform of prion protein binder which comprises lactoferrin; and a method for detecting pathogenic isoform of prion protein by using the pathogenic isoform of prion protein binder.
Claims4
A method for detecting a pathogenic isoform of a prion protein, comprising:
- bringing a sample into contact with lactoferrin;
- separating a bound component from the lactoferrin brought into contact with the sample;
- and
- detecting a pathogenic isoform of a prion protein contained in the component separated from the lactoferrin.
A method for isolating a pathogenic isoform of a prion protein, comprising:
- bringing a sample into contact with lactoferrin;
- and
- separating a bound component from the lactoferrin brought into contact with the sample.
Dependencies are inferred from the claim text.