Method for preparing standardized serum mixture for determining allergen potency and the use thereof
AssigneeZhejiang Wolwo Bio-Pharmaceutical Co., Ltd.
InventorGengxi Hu
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Abstract
A method for preparing standardized serum mixture for determining allergen potency which comprises: 1) providing multiple serum samples from patients moderately hypersensitive to said allergen; 2) determining the relative content of sIgE against said allergen in each serum sample, obtaining the mean value of the relative content of sIgE of said multiple serum samples, and obtaining deviation value of the relative content of sIgE of each serum with respect to said mean value; 3) removing at least 5% of serum samples that have the largest and smallest deviation values respectively, and mixing the residual sera in the same volume. A serum mixture prepared by the method as well as the use of such serum mixture are also described.
Claims13
A method for preparing a serum mixture which is used for determining potency of an allergen, wherein the method comprises the following steps:
- 1) providing multiple serum samples from individuals moderately hypersensitive to said allergen;
- 2) determining a relative content of an allergen specific IgE of each serum sample from said multiple serum samples, obtaining a mean value of the relative content of the allergen specific IgE of said multiple serum samples, and obtaining a deviation value of the relative content of the allergen specific IgE of the serum sample, the deviation value being calculated with the relative content of the serum sample and the mean value of said multiple serum samples;
- and
- 3) removing at least 5% of said multiple serum samples that have the largest and smallest deviation values respectively, and mixing the residual serum samples at the same volume.
Dependencies are inferred from the claim text.