Hollow sphere from amphiphilic chitosan derivatives and method of preparing amiphiphilic chitosan derivative complex for medical use
AssigneeNational Chiao Tung University
InventorsSan-Yuan Chen, Kun-Ho Liu, Dean-Mo Liu
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Abstract
A hollow sphere from amphiphilic chitosan derivatives and a method of preparing an amphiphilic chitosan derivative complex for medical use are disclosed, and the hollow sphere from amphiphilic chitosan derivatives comprises: chitosan derivatives represented by the following formula (I), which self-assemble and form a hollow sphere in a solvent; wherein, each R1 is independently hydrogen, C1˜C4 alkyl, C1˜C6 carboxyl, sulfate group, or phosphate group, each R2 is independently hydrogen, C1˜C12 alkyl, C1˜C6 carboxyl, or C2˜C12 acyl group, and m is an integer of 100-2000.
Claims10
A hollow sphere from amphiphilic chitosan derivatives comprising:
- a shell which is composed of chitosan derivatives in a layer structure, wherein the chitosan derivatives are compounds represented by the following formula (II), which self-assemble and form a hollow sphere in a solvent
- wherein, each R3 independently is C5˜C11 alkyl;
- and x, y, z, n, and p independently are integrals of 20˜2000.
Dependencies are inferred from the claim text.