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US 8,263,120 B2Granted
Oral antimicrobial pharmaceutical compositions
AssigneeCosmo Technologies Limited
InventorsMauro Ajani, Roberta Bozzella, Giuseppe Celasco, Roberto Villa
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Abstract
The present invention relates to oral pharmaceutical compositions with controlled and/or programmed release containing at least one active ingredient having antimicrobial and/or anti-infectious activity for the treatment of infections of the large intestine, in particular the colon.
Claims11
A controlled release oral pharmaceutical composition comprising:
- (1) a tablet core comprising:
- a) rifamycin SV in an amount effective for the treatment of an infection of the colon;
- b) a lipophilic substance having a melting point less than about 90° C.;
- c) lecithin;
- and
- d) a hydrophilic substance comprising a carboxyvinyl polymer or carboxyvinyl copolymer;
- and
- (2) a coating on said tablet core, said coating comprising a gastro-resistant substance.
5 more elements
Dependencies are inferred from the claim text.