Bioresorbable fillers constituted by phospholipid liposomes and hyaluronic acid and/or the derivatives thereof
AssigneeFidia Farmaceutici S.P.A.
InventorsLanfranco Callegaro, Devis Galesso, Anna Taglienti
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Abstract
The present invention describes a new bioresorbable filler constituted by hyaluronic acid and/or the derivatives thereof structured with/in phospholipid liposomes, which increase the residence time of the starting polymer in situ. Said fillers described herein are substantially intended to increase the soft tissues in aesthetic surgery and dermocosmetics for the correction of mild to medium defects, but because of their special characteristics they can also be used in other fields of application.
Claims15
A method of treating osteoarthrosis comprising intra-articularly administering to a patient in need thereof an effective amount of a pharmaceutical composition comprising:
- a hyaluronic acid and/or derivitized hyaluronic acid;
- and
- liposomes comprising a phospholipid,
- wherein said composition contains encapsulated hyaluronic acid and hyaluronic acid forming tubular structures between liposomes, which tubular structures are encapsulated in lipid bilayers, thereby treating the osteoarthrosis.
A method of skin soft tissue filling comprising:
- Administering to a patient, at the site to be filled, an effective amount of a pharmaceutical composition comprising:
- A hyaluronic acid and/or derivitized hyaluronic acid;
- and
- liposomes comprising a phospholipid,
- wherein said composition contains encapsulated hyaluronic acid and hyaluronic acid forming tubular structures between liposomes, which tubular structures are encapsulated in lipid bilayers, thereby filling the skin soft tissue.
A method for skin soft tissue filling which comprises:
- administering to a patient, at the site to be filled, a hexadecyl amide of hyaluronic acid and phospholipid liposomes as a composition, wherein said composition contains encapsulated hexadecyl amide of hyaluronic acid forming tubular structures between liposomes, which tubular structures are encapsulated in lipid bilayers, and wherein said phospholipid is dipalmitoylphosphatidylcholine (DPPC), thereby filling the skin soft tissue.
Dependencies are inferred from the claim text.