Methods for producing silver-bonded antimicrobial moist wound dressings and moist wound dressings produced by the methods

A method for producing a silver-bonded antimicrobial moist wound dressing, comprising the steps of:

• adding silver chloride (AgCl) to a 0.1-30% NH4OH aqueous solution to dissociate silver ions from the silver chloride to obtain a silver-ion containing solution, wherein the silver chloride is added in an amount of 0.00001% to 20.0% (w/v);
• dissolving sodium carboxymethyl cellulose (C6H9OCH2COONa, CMC-Na) in water or an organic solvent to obtain a CMC solution, wherein the concentration of the CMC solution ranges between 2% and 15% (w/v);
• mixing the silver ion-containing solution with the CMC solution so that the hydrogen ions (H+) of the hydroxyl groups of the CMC are replaced by the silver ions to prepare a silver-CMC compound;
• wherein, after mixing, the solutions are maintained at a temperature of 20° C. to 50° C. for 10 seconds to 1 hour;
• and
• wherein the amount of the CMC ranges between 0.005 g/ml and 0.035 g/ml of the silver ion-containing solution;
• dispersing and absorbing the silver-CMC compound in a medium;
• and
• drying the medium.