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US 8,263,104 B2Granted
Polymer nanofilm coatings
AssigneesNorthwestern University, The Regents of the University of California
InventorsDean Ho, Mark Chen, Erik Pierstorff, Houjin Huang, Edward K Chow, Genhong Cheng
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Abstract
Disclosed herein are nanofilm coatings for implantable medical devices comprising a diblock or triblock copolymer (PEO-PMMA or PMOXA-PDMS-PMOXA, respectively). Such nanofilms, may be used, for example, as amphiphilic supports for therapeutic agents. These materials are conducive towards the formation of active substrates for a suite of biological and medical applications.
Claims6
An implantable medical device having one or more of its surfaces coated with a nanofilm composition comprising:
- (a) a first layer comprising parylene;
- (b) a second layer comprising a copolymer;
- and
- (c) a third layer comprising nanoporous parylene,
- wherein the copolymer is a triblock copolymer comprising polymethyloxazoline-polydimethylsiloxane-polymethyloxazoline, and wherein the nanofilm has a thickness between 0.1 nm and 20 nm.
2 more elements
Dependencies are inferred from the claim text.