Compounds and methods for treatment and diagnosis of chlamydial infection
AssigneeCorixa Corporation
InventorsAjay Bhatia, Yasir A. W. Skeiky, Peter Probst
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Abstract
Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
Claims12
An immunogenic composition comprising an immunostimulant and a polypeptide, said polypeptide comprising:
- (i) an amino acid sequence having at least 90% identity to the entire length of the sequence of SEQ ID NO:
- 178;
- or
- (ii) an immunogenic fragment of the sequence of SEQ ID NO:
- 178.
Dependencies are inferred from the claim text.