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US 8,263,087 B2Granted
Compositions and methods for vaccinating against HSV-2
AssigneesVical Incorporated, University of Washington
InventorsAdrian Vilalta, Michal Margalith, Lichun Dong, David M. Koelle
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Abstract
This invention relates to a method for systemic immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in a mammal. The method is particularly effective for protecting a mammal from herpes simplex virus. Also disclosed are therapeutic compositions useful in such a method.
Claims11
An isolated polynucleotide consisting of SEQ ID NOS:
- 9, 11 and 12, wherein the polynucleotide encodes amino acids of a herpes simplex virus polypeptide.
Dependencies are inferred from the claim text.