SlpA as a tool for recombinant protein and enzyme technology
AssigneeRoche Diagnostics Operations, Inc.
InventorsChristian Scholz, Elke Faatz, Urban Schmitt, Peter Schaarschmidt
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AssigneeRoche Diagnostics Operations, Inc.
InventorsChristian Scholz, Elke Faatz, Urban Schmitt, Peter Schaarschmidt
Estimating the term…
Disclosed are a recombinant DNA molecule encoding a fusion protein comprising a SlpA chaperone and a target polypeptide wherein human FK506 binding proteins (FKBPs) are excluded as target polypeptides, a corresponding expression vector encoding said fusion protein as well as host cells transformed with said expression vector. Also disclosed are a method for producing the fusion protein, a recombinantly produced fusion protein comprising a SlpA chaperone and a target polypeptide. A further aspect of the invention is the use of the recombinantly produced fusion protein, and a reagent kit containing a recombinantly produced fusion protein comprising a SlpA chaperone and a target polypeptide.
A recombinant fusion protein comprising an E. coli SlpA chaperone polypeptide sequence and a target polypeptide, wherein the target polypeptide comprises a herpes simplex virus 1 (HSV-1) antigen gG1.
A recombinant fusion protein comprising an E. coli SlpA chaperone polypeptide sequence and a target polypeptide, wherein the target polypeptide comprises at least one of a herpes simplex virus 1 (HSV-1) antigen gG1 and a herpes simplex virus 2 (HSV-2) antigen gG2.
Dependencies are inferred from the claim text.