Combination therapy with antibody-drug conjugates
AssigneeSeattle Genetics, Inc.
InventorsEzogelin Oflazoglu, Eric Sievers, Hans-Peter Gerber
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Abstract
Methods for the treatment of Hodgkin's lymphoma comprising administering both a chemotherapeutic regimen and an antibody-drug conjugate compound to a subject in need thereof are provided.
Claims13
A method for treating Hodgkin lymphoma in a subject, the method comprising administering to a subject in need thereof a chemotherapeutic regimen comprising doxorubicin, bleomycin, vinblastine and dacarbazine and an antibody-drug conjugate compound, wherein said antibody-drug conjugate is an anti-CD30 antibody conjugated to an auristatin compound and administration of said antibody-drug conjugate compound and chemotherapeutic regimen provides a synergistic effect in the treatment of Hodgkin lymphoma in the patient.
Dependencies are inferred from the claim text.