Topical anesthetic for dental procedures
OwnerAlan J. Wickenhauser, Stephen E. Peipertinventors
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Abstract
A topical anesthetic for dental procedures is provided containing about 3 wt % to 10 wt % tetracaine in a vehicle suitable for administration to the oral mucosa. The vehicle for transporting the tetracaine includes a water soluble mucoadhesive or a combination of mucoadhesives such as a high molecular weight poly(ethylene oxide) homopolymer and a cellulose polymer. The vehicle may additionally include a penetration enhancer such as propylene glycol. The tetracaine is ground into a powder and is suspended in a plasticized hydrocarbon gel which completes the vehicle.
Claims5
A topical anesthetic for use in producing local anesthesia in about three to five minutes when applied to the oral mucosa prior to a dental treatment, said topical anesthetic comprising tetracaine base in an amount from about 4 wt % to about 8 wt % of the topical anesthetic in a non-aqueous vehicle, wherein the non-aqueous vehicle comprises a high molecular weight poly(ethylene oxide) homopolymer in combination with a cellulose polymer, wherein the combination makes up about 10 wt % of the topical anesthetic, and said high molecular weight poly(ethylene oxide) homopolymer is present in an amount from about 3 wt % to about 8 wt % of the combination;
- propylene glycol in an amount from about 5 wt % to 15 wt % of the topical anesthetic;
- and a plasticized hydrocarbon gel in an amount of about 70 wt % of the topical anesthetic, said topical anesthetic being stable under refrigeration for at least six months as to efficacy and potency of the tetracaine base as an anesthetic.
Dependencies are inferred from the claim text.