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US 8,263,043 B2Granted
Cellular labeling and quantification for nuclear magnetic resonance techniques
AssigneeCarnegie Mellon University
InventorsEric T. Ahrens, Mangala Srinivas
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Abstract
The disclosure provides, in part, a method for quantifying cell numbers in vivo. The disclosure comprises a method of quantifying labeled cells by nuclear magnetic resonance techniques and a computer method for the same.
Claims33
A method for quantifying cell number in vivo, the method comprising:
- a. administering to a subject cells that are labeled with a fluorocarbon imaging reagent, wherein at least a portion of the fluorocarbon imaging reagent was internalized into the cell;
- b. examining at least a portion of the subject by 19F magnetic resonance imaging (MRI), thereby detecting the cells that are labeled with the fluorocarbon imaging reagent in the subject;
- and
- c. quantifying the number of labeled cells in a region of interest (ROI).
1 more element
Dependencies are inferred from the claim text.