Analytical cartridge with fluid flow control
AssigneeMicropoint Bioscience, Inc.
InventorsZhiliang Wan, Nan Zhang
Life of this patent
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Abstract
Analytical cartridges, systems and methods of processing a sample for analysis using capillary flows. Vertical gradient sample filtration provides filtrate to an incubation chamber for a time controlled by a flow modulator at the outlet of the incubation chamber. The flow modulator can include a serpentine capillary flow path without side walls. Incubated filtrate can flow from the incubation chamber to a detection channel after a predetermined time. The detection chamber can include one or more analytical regions in a porous substrate for detection of two or more analytes on the same cartridge from the same sample.
Claims14
A cartridge comprising:
- a first chamber;
- a flow modulator comprising a fluid flow path defined by opposing top and bottom path surfaces, wherein the flow path does not comprise solid lateral side walls;
- a lateral space adjacent to the flow path and in fluid contact along the flow path, and,
- a second chamber;
- wherein, the lateral space comprises upper and lower lateral space surfaces separated by a distance greater than a spacing distance between opposing top and bottom flow path surfaces, whereby a fluid flowing from the first chamber flows along the flow path and surface tension of the fluid does not allow the fluid to flow laterally out from the flow path.
Dependencies are inferred from the claim text.