Process for production of benzaldehyde compound
AssigneeSuitomo Chemical Company, Limited
InventorKoichi Nakazawa
Life of this patent
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Abstract
A benzaldehyde acetal compound of formula (3): (wherein Q represents a hydrogen atom or a halogen atom, Ar represents a phenyl group optionally substituted with at least one selected from the group consisting of alkyl groups having 1 to 4 carbon atoms and halogen atoms, and R represents an alkyl group having 1 to 4 carbon atoms).
Claims23
A benzaldehyde acetal compound of formula (3):
- (wherein Q represents a hydrogen atom or a halogen atom, Ar represents a phenyl group optionally substituted with at least one selected from the group consisting of alkyl groups having 1 to 4 carbon atoms and halogen atoms, and R represents an alkyl group having 1 to 4 carbon atoms).
A method for producing a benzaldehyde compound of formula (4):
- (wherein Q and Ar respectively represent the same meanings as described below), which comprises reacting a benzaldehyde acetal compound of formula (3):
- (wherein Q represents a hydrogen atom or a halogen atom, Ar represents a phenyl group optionally substituted with at least one selected from the group consisting of alkyl groups having 1 to 4 carbon atoms and halogen atoms, and R represents an alkyl group having 1 to 4 carbon atoms) with water in the presence of an acid.
A method for producing a benzaldehyde dialkylacetal compound of formula (3):
- (wherein Q, Ar and R respectively represent the same meanings as described below) which comprises reacting a benzal halide compound of formula (1):
- (wherein Q represents a hydrogen atom or a halogen atom, X represents a halogen atom and Ar represents a phenyl group optionally substituted with at least one selected from the group consisting of alkyl groups having 1 to 4 carbon atoms and halogen atoms) with an alkali metal alkoxide of formula (2):
- RO—M (2)
- (wherein R represents an alkyl group having 1 to 4 carbon atoms and M represents an alkali metal atom).
A benzal halide compound of formula (1):
- (wherein Q represents a hydrogen atom or a halogen atom, X represents a halogen atom and Ar represents a phenyl group optionally substituted with at least one selected from the group consisting of alkyl groups having 1 to 4 carbon atoms and halogen atoms).
A method for producing a benzal halide compound of formula (1):
- (wherein Q, X and Ar respectively represent the same meanings as described below),
- which comprises reacting a benzal halide compound of formula (5):
- (wherein Q and X respectively represent the same meanings as described above) with a phenol compound of formula (6):
- Ar—OH (6)
- (wherein Ar represents the same meaning as described above) in the presence of a base.
A method for producing a benzaldehyde compound, which comprises
- (A) a step of reacting a benzal halide compound of formula (1):
- (wherein Q represents a hydrogen atom or a halogen atom, X represents a halogen atom and Ar represents a phenyl group optionally substituted with at least one selected from the group consisting of alkyl groups having 1 to 4 carbon atoms and halogen atoms) with an alkali metal alkoxide of formula (2):
- RO—M (2)
- (wherein R represents an alkyl group having 1 to 4 carbon atoms and M represents an alkali metal atom)
- to give a benzaldehyde dialkylacetal compound of formula (3):
- (wherein Q, Ar and R respectively represent the same meanings as described above), and
- (B) a step of reacting the benzaldehyde dialkylacetal compound of formula (3) with water in the presence of an acid to give a benzaldehyde compound of formula (4):
- (wherein Q and Ar respectively represent the same meanings as described above).
Dependencies are inferred from the claim text.