Collagenolytic active enzyme containing compositions, and their use in the dental field
Assignee3M Deutschland GmbH
InventorsOliver Kappler, Ingo R. Haeberlein
Life of this patent
Estimating the term…
Abstract
The invention relates to a composition comprising at least one collagenolytic active enzyme with enzymatic activity at acidic pH for drilless enzymatic caries removal. Furthermore, the present invention relates to a process of producing this collagenolytic active enzyme comprising composition and to processes of removing caries. The invention also relates to the use of collagenolytic active enzyme comprising compositions for producing a treatment agent for dental applications.
Claims19
A method of caries removal comprising the step of applying a composition to a tooth, said composition comprising:
- one or more collagenolytic active enzymes;
- at least one solvent;
- at least one additive;
- and
- at least one acid,
- wherein at least one collagenolytic active enzyme is a serine-carboxyl proteinase, and wherein said composition has a collagenolytic activity of more than 5 units per milliliter and a pH value of about 1 to about 5.
A method of caries removal comprising the step of applying a composition to a tooth, said composition comprising:
- at least one collagenolytic active enzyme selected from the group consisting of Kumamolysin and ScP-A;
- at least one solvent;
- at least one additive;
- at least one acid;
- and
- pepsin,
- wherein said composition has a collagenolytic activity of more than 5 units per milliliter and a pH value of about 1 to about 5.
Dependencies are inferred from the claim text.