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US 8,246,805 B2Granted
Micro-fluidic chip and flow sending method in micro-fluidic chip
AssigneeSony Corporation
InventorMasataka Shinoda
Life of this patent
Estimating the term…
Abstract
Disclosed herein is a micro-fluidic chip including a hollow area into which a charged droplet is introduced, and an electrode configured to be provided toward the hollow area. Movement direction of a droplet in the hollow area is controlled based on electric force acting between a charge given to the droplet and the electrode.
Claims11
A micro-fluidic chip comprising:
- a hollow area into which a charged droplet is introduced;
- and
- an electrode configured to be provided toward the hollow area;
- wherein
- movement direction of a droplet in the hollow area is controlled based on electric force acting between a charge given to the droplet and the electrode;
- a plurality of branch areas configured to communicate with the hollow area;
- wherein
- the droplet is led to one branch area that is arbitrarily selected by controlling the movement direction of the droplet in the hollow area;
- a flow channel configured to send a liquid into the hollow area;
- and
- a fluid inlet configured to meet the flow channel at least from one side of the flow channel and introduce a fluid that is a gas or an insulating liquid into the flow channel;
- wherein
- a liquid passing through the flow channel is segmented to be turned to a droplet by a fluid introduced from the fluid inlet and is sent into the hollow area;
- a microtube configured to introduce a first liquid into a laminar flow of a second liquid passing through the flow channel;
- wherein
- the first liquid and the second liquid are sent to the communicating port of the flow channel or a confluence of the fluid inlet in such a way that a laminar flow of the first liquid introduced from the microtube is surrounded by the laminar flow of the second liquid;
- the flow channel has a narrowing part that is so formed that area of a section of the narrowing part perpendicular to liquid sending direction gradually decreases;
- and
- the first liquid and the second liquid are so sent that laminar flow widths of the laminar flows of the first liquid and the second liquid are narrowed in the narrowing part.
16 more elements
A liquid analysis device comprising:
- a micro-fluidic chip including
- a hollow area into which a charged droplet is introduced;
- and
- an electrode configured to be provided toward the hollow area;
- wherein
- movement direction of a droplet in the hollow area is controlled based on electric force acting between a charge given to the droplet and the electrode;
- a plurality of branch areas configured to communicate with the hollow area;
- wherein
- the droplet is led to one branch area that is arbitrarily selected by controlling the movement direction of the droplet in the hollow area;
- a flow channel configured to send a liquid into the hollow area;
- and
- a fluid inlet configured to meet the flow channel at least from one side of the flow channel and introduce a fluid that is a gas or an insulating liquid into the flow channel;
- wherein
- a liquid passing through the flow channel is segmented to be turned to a droplet by a fluid introduced from the fluid inlet and is sent into the hollow area;
- a microtube configured to introduce a first liquid into a laminar flow of a second liquid passing through the flow channel;
- wherein
- the first liquid and the second liquid are sent to the communicating port of the flow channel or a confluence of the fluid inlet in such a way that a laminar flow of the first liquid introduced from the microtube is surrounded by the laminar flow of the second liquid;
- the flow channel has a narrowing part that is so formed that area of a section of the narrowing part perpendicular to liquid sending direction gradually decreases;
- and
- the first liquid and the second liquid are so sent that laminar flow widths of the laminar flows of the first liquid and the second liquid are narrowed in the narrowing part.
17 more elements
A microparticle sorting device comprising:
- a hollow area into which a charged droplet including a microparticle is introduced;
- and
- an electrode configured to be provided toward the hollow area;
- wherein
- movement direction of a droplet in the hollow area is controlled based on electric force acting between a charge given to the droplet and the electrodes
- a plurality of branch areas configured to communicate with the hollow area;
- wherein
- the droplet is led to one branch area that is arbitrarily selected by controlling the movement direction of the droplet in the hollow area;
- a flow channel configured to send a liquid into the hollow area;
- and
- a fluid inlet configured to meet the flow channel at least from one side of the flow channel and introduce a fluid that is a gas or an insulating liquid into the flow channel;
- wherein
- a liquid passing through the flow channel is segmented to be turned to a droplet by a fluid introduced from the fluid inlet and is sent into the hollow area;
- a microtube configured to introduce a first liquid into a laminar flow of a second liquid passing through the flow channel;
- wherein
- the first liquid and the second liquid are sent to the communicating port of the flow channel or a confluence of the fluid inlet in such a way that a laminar flow of the first liquid introduced from the microtube is surrounded by the laminar flow of the second liquid;
- the flow channel has a narrowing part that is so formed that area of a section of the narrowing part perpendicular to liquid sending direction gradually decreases;
- and
- the first liquid and the second liquid are so sent that laminar flow widths of the laminar flows of the first liquid and the second liquid are narrowed in the narrowing part.
16 more elements
A flow sending method in a micro-fluidic chip, the method comprising the steps of:
- introducing a charged droplet into a hollow area provided in the micro-fluidic chip;
- and
- controlling movement direction of the droplet in the hollow area based on electric force acting between an electrode provided toward the hollow area and a charge given to the droplet;
- wherein the droplet is led to any one branch area selected from a plurality of branch areas communicating with the hollow area by controlling the movement direction of the droplet in the hollow area;
- wherein a liquid is turned to a droplet by using a piezoelectric element at a communicating port, to the hollow area, of a flow channel that sends the liquid the hollow area and simultaneously a charge is given to the liquid form a charged droplet and send the charged droplet into the hollow area;
- and
- wherein a liquid passing through a flow channel that sends the liquid into the hollow area is segmented and turned to a droplet by introducing a fluid that is a gas or an insulating liquid into the flow channel and simultaneously a charge is given to the liquid form a charged droplet and send the charged droplet into the hollow area.
4 more elements
Dependencies are inferred from the claim text.