Materials and methods to potentiate cancer treatment

A compound having the formula,

• wherein:
• A is
• B is aryl or a nitrogen-containing heteroaryl;
• R9 is H or OH;
• R10 is H, O-alkyl or CN;
• and
• R3 is hydrogen or ORh;
• wherein Rb is hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, heteroaryl, or substituted heteroaryl, and Rh, independently, is hydrogen, alkyl, substituted alkyl, cycloalkyl, aryl, substituted aryl, heteroaryl, or substituted heteroaryl;
• wherein said substituted alkyl is an alkyl group with one substituent or more than one substituent bound to the same carbon or different carbons,
• wherein each substituent is independently selected from the group consisting of cycloalkyl, aryl, heteroaryl, heterocyclic, substituted aryl, substituted heteroaryl, substituted heterocyclic, N(Rh′)2, ORh′, SRh′, sulfoxide, sulfonyl, halo, carboxyl, acyl, carboxy, hydrazino, hydrazono, and hydroxyamino, wherein each Rh′, independently, is hydrogen, alkyl, cycloalkyl, aryl, or heteroaryl,
• or a pharmaceutically acceptable salt thereof.