Methods and compositions for heavy metal detoxification
AssigneeMetaproteomics, LLC
InventorsMatthew L. Tripp, Veera Konda, Amy Hall, Anu Desai, Jeffrey S. Bland
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Abstract
Compositions and methods for enhancing heavy metal detoxification are described. The compositions and methods described provide enhanced activity of key detoxification systems including that the induction of phase II detoxification enzymes, such as glutathione S-transferases (GSTs), and NADPH quinone reductase (NQO1) activity.
Claims12
A composition for promoting heavy metal detoxification in a mammal in need thereof, said composition comprising (a) from about 0.10 to about 10.00 grams of spent hops;
- (b) from about 5 to about 1200 mg of 1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione;
- (c) from about 0.10 to about 24 mg of zinc;
- and (d) from about 5 to about 1200 mg of 3-(2-(Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenenaphthyl)ethylidene)dihydro-4-hydroxyfuran-2(3H)-one.
A method for promoting heavy metal detoxification in a mammal in need thereof comprising administering to the mammal a composition comprising (a) from about 0.10 to about 10.00 grams of spent hops;
- (b) from about 5 to about 1200 mg of 1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione;
- (c) from about 0.10 to about 24 mg of zinc;
- and (d) from about 5 to about 1200 mg of 3-(2-(Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenenaphthyl)ethylidene)dihydro-4-hydroxyfuran-2(3H)-one.
Dependencies are inferred from the claim text.