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AssigneeCaldera Pharmaceuticals, Inc.
InventorsEva R. Birnbaum, Benjamin P. Warner, Sharon M. Baldwin, Jennifer A. Berger, Rebecca L. E. Miller
Estimating the term…
The present invention includes an apparatus for preparing samples for measurement by x-ray fluorescence spectrometry. The apparatus comprises a plate having one or more holes passing through the plate. The holes are covered by a film on one side of the plate. The holes are less than 500 micrometers across in one dimension where the film covers the holes. The film is translucent to x-rays. The present invention also includes an apparatus for preparing samples for measurement by x-ray fluorescence spectrometry. The apparatus comprises a plate having one or more holes passing through the plate. The holes are covered on one side of the plate by a detachable cover forming a water-tight seal against the plate. The cover is substantially free of the elements osmium, yttrium, iridium, phosphorus, zirconium, platinum, gold, niobium, mercury, thallium, molybdenum, sulfur, lead, bismuth, technetium, ruthenium, chlorine, rhodium, palladium, argon, silver, and thorium. The holes are less than about 500 micrometers across in one dimension where the cover covers the holes. The present invention also includes a method for preparing samples for measurement by x-ray fluorescence spectrometry. The method comprises providing a solution of with less than 10 micromolar solute and a volume of between about 2 microliters and about 2 milliliters. The solution is concentrated and analyzed using x-ray fluorescence spectrometry.
A method for preparing a sample for measurement by x-ray fluorescence spectrometry, comprising providing a solution having a concentration of solute less than 10 micromolar and a volume of between 2 microliters and 2 milliliters, concentrating the solution into a sample having less than one-fifth of the original volume of the solution, and analyzing the sample using x-ray fluorescence spectrometry.
A method for preparing a sample for measurement by x-ray fluorescence spectrometry, comprising providing a solution having a concentration of solute less than 10 micromolar and a volume of between 2 microliters and 2 milliliters, and concentrating the solution into a sample having less than one-fifth of the original volume of the solution, wherein the solution comprises a biological molecule having a concentration of less than about 10 micromolar.
Dependencies are inferred from the claim text.