Method and device for diagnosing chronic fatigue syndrome (CFS) by using near infrared spectrum
AssigneesFatigue Science Laboratory Inc., Osaka University, Hirohiko Kuratsune
InventorsHirohiko Kuratsune, Akikazu Sakudo, Kazuyoshi Ikuta
Life of this patent
Estimating the term…
Abstract
The present invention provides a method and device of quantitatively or qualitatively examining and diagnosing chronic fatigue syndrome (CFS) by: irradiating a sample derived from an examinee or other animal with light having a wavelength in a range of 400 nm to 2500 nm or a wavelength in part of the range; detecting reflected light, transmitted light, or transmitted and reflected light to obtain an absorption spectral data; and analyzing absorbance at all measurement wavelengths or at specific wavelengths in the absorption spectral data by using an analytical model prepared beforehand.
Claims15
A method of quantitatively or qualitatively examining and judging chronic fatigue syndrome comprising:
- irradiating a sample derived from an animal with light comprising a continuous wavelength spectrum from 600 nm to 1100 nm,
- measuring an absorption spectrum of a light selected from the group consisting of reflected light, transmitted light, and transmitted and reflected light,
- generating absorption spectral data from the absorption spectrum,
- analyzing the absorption spectral data with multivariate analysis, and
- comparing the multivariate analysis with an analytical model to determine chronic fatigue syndrome in the animal;
- wherein the analytical model comprises data correlating differences in multivariate analysis of absorption spectral data between a normal animal and an animal with chronic fatigue syndrome, and detecting if the absorption spectral data from the sample correlates with the absorption spectral data for the animal with chronic fatigue syndrome.
A test and diagnostic device, comprising:
- a means for irradiating a sample derived from an animal with a light comprising a continuous wavelength spectrum from 400 nm to 2500 nm,
- a means for carrying out spectroscopy, wherein the spectroscopy is selected from the group consisting of prespectroscopy and postspectroscopy,
- a means for measuring an absorption spectrum from light selected from the group consisting of reflected light, transmitted light, and transmitted and reflected light with respect to the light comprising a continuous wavelength spectrum from 400 nm to 2500 nm with which the sample was irradiated,
- a means for generating absorption spectral data from the absorption spectrum, and
- a means for analyzing the absorption spectral data of the sample with multivariate analysis and comparing the multivariate analysis with an analytical model to determine chronic fatigue syndrome in the animal;
- wherein the analytical model comprises data correlating differences in multivariate analysis of absorption spectral data between a normal animal and an animal with chronic fatigue syndrome, and detecting if the absorption spectral data from the sample correlates with the absorption spectral data for the animal with chronic fatigue syndrome patients.
A non-transitory memory storage medium containing machine readable program code, which, when executed by a processor, causes said processor to perform the process of:
- generating an analytical model to analyze absorption spectral data from an absorption spectrum of a light of a sample irradiated with light comprising a continuous wavelength spectrum from 600 nm to 1100 nm with a multivariate analysis to determine chronic fatigue syndrome in an animal;
- wherein the analytical model comprises data correlating differences in multivariate analysis of absorption spectral data between a normal animal and an animal with chronic fatigue syndrome,
- determining if absorption spectral data from a sample correlates with absorption spectral data from an animal with chronic fatigue syndrome, and
- analyzing absorption spectral data of a sample with multivariate analysis and comparing the multivariate analysis with an analytical model to determine chronic fatigue syndrome in an animal.
Dependencies are inferred from the claim text.