Compositions for and methods of enhancing the immune response to antigens
AssigneeWittycell
InventorVincent Serra
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Abstract
Compositions comprising the compound of formula are provided herein. Also provided are methods of enhancing an immune response of a subject to an antigen by administering the antigen and the composition. The enhanced immune response may be an humoral immune response, a CD4+ T cell response, a CD8+ T cell response or result in activation of antigen presenting cells. Methods of enhancing the immune response by intramuscular administration of an antigen and the composition including the compound of formula I are also provided.
Claims27
A method of enhancing an immune response of a subject to an antigen comprising administering an antigen and a composition comprising a compound of formula I:
- wherein R1 is H or —OH, R2 is —H or —OH, x is an integer from 18 to 26, and n is an integer from 10 to 15, to the subject, wherein the immune response of the subject to the antigen is enhanced relative to an immune response of a control to the antigen.
Dependencies are inferred from the claim text.