Methods of controlling proliferation and differentiation of stem and progenitor cells
AssigneesGamida Cell Ltd., Hadasit Medical Research Services and Development Ltd.
InventorsTony Peled, Eitan Fibach, Avi Treves
Life of this patent
Estimating the term…
Abstract
A method of ex-vivo expanding a population of stem cells, while at the same time inhibiting differentiation of the stem cells. The method comprises ex-vivo providing the stem cells with conditions for cell proliferation and with at least one copper chelator in an amount and for a time period for permitting the stem cells to proliferate and, at the same time, for reducing a capacity of the stem cells to differentiate.
Claims6
A method of expanding a population of mesenchymal stem or progenitor cells, the method comprising providing the cells with conditions for cell proliferation and, at the same time, reducing a capacity of said cells in utilizing copper.
Dependencies are inferred from the claim text.