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US 8,188,074 B2Granted
Biologically active methylene blue derivatives
AssigneePhotopharmica Limited
InventorsStanley Beames Brown, Cassandra Claire O'Grady, John Griffiths, Kirste Joanne Mellish, David Ian Vernon
Life of this patent
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Abstract
The present invention relates to a composition which includes a moiety of formula wherein R1, R2, R3 and R4 each represent n-pentyl, and to a method of sterilizing a su fluid using same.
Claims15
A composition comprising a compound of formula
- wherein R1, R2, R3 and R4 each represent n-pentyl, and wherein XP− is a counteranion and P is 1, 2 or 3,
- together with a diluent or an excipient, said composition including liposomes, nano-particles, colloidal suspensions, micelles, micro-emulsions, vesicles or nano-spheres.
A composition comprising a compound of formula
- wherein R1, R2, R3 and R4 each represent n-pentyl, and wherein XP− is a counteranion and P is 1, 2 or 3, and which includes a delivery vehicle or excipient selected from alcohols, dimethyl sulphoxide, water, saline, solubilisers, isotonising agents, pH regulators, dyes, gelling agents, thickeners, buffers and combinations thereof.
A composition comprising a compound of formula
- wherein R1, R2, R3 and R4 each represent n-pentyl, and wherein XP− is a counteranion and P is 1, 2 or 3,
- together with a diluent or an excipient, wherein said compound is present at a concentration in the range of 100 μM to 30 mM.
A composition comprising a compound of formula
- wherein R1, R2, R3 and R4 each represent n-pentyl, and wherein XP is a counteranion and P is 1, 2 or 3, and
- wherein said compound is present at a concentration in the range of 0.0005 to 20 wt %.
A composition comprising a compound of formula
- wherein R1, R2, R3 and R4 each represent n-pentyl, and wherein XP− is a counteranion and P is 1, 2 or 3, and wherein said compound is present at a concentration in the range of 0.0005 to 20 wt %.
Dependencies are inferred from the claim text.