Woven and/or braided fiber implants and methods of making same
AssigneeShriners Hospitals for Children
InventorsThomas J. Koob, Tian Davis, Douglas Pringle
Life of this patent
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Abstract
Bioprosthesis having an implantable braided or woven construct with a plurality of collagen-derived fibers interlocked or interlaced together. The braided or woven constructs can be flexible and resorbable. The braided or woven constructs can have the dynamic flexibility, tensile strength and stiffness suitable for tendon or ligament repairs. The braided or woven construct may be used for ulnar collateral ligament reconstruction.
Claims43
An implantable bioprosthesis, comprising:
- an implantable construct consisting essentially of a plurality of NDGA polymerized collagen fibers, wherein the NDGA polymerized collagen fibers have a tensile strength that is between about 180-350 MPa and are arranged into bundles of substantially parallel fibers, with each of the bundles comprising at least two NDGA polymerized collagen fibers, wherein the bundles are braided and woven or braided or woven together, and wherein the construct has tensile strength, stiffness and dynamic flexibility that meets or exceeds that of a pre-injury natural ligament or tendon.
A medical kit for a tendon or ligament repair, augmentation or replacement, comprising:
- a construct consisting essentially of elongate high-strength NDGA polymerized collagen fibers, wherein the elongate high-strength NDGA polymerized collagen fibers have a tensile strength that is between about 180-350 MPa and are arranged into bundles of substantially parallel fibers, wherein the bundles are braided and woven or braided or woven together, and wherein the construct has tensile strength, stiffness and dynamic flexibility that meets or exceeds that of a pre-injury natural ligament or tendon;
- and a sterile package sealably enclosing the braided or woven fiber construct therein.
An implant, comprising:
- an implantable construct consisting essentially of 81 NDGA-polymerized collagen fibers having a tensile strength that is between about 180-350 MPa and substantially the same diameter, wherein the with 81 fibers are arranged as nine bundles of nine parallel fibers each, wherein each bundle is represented by a corresponding number 1, 2, 3, 4, 5, 6, 7, 8, and 9, respectively, and wherein the nine bundles have a repeating braid pattern defined by the following sequence:
- 2 3 4 5 6 1 8 9 7
- 3 4 2 6 1 8 9 7 5
- 4 2 6 1 8 3 7 5 9
- 2 6 4 8 3 7 5 9 1
- 6 4 8 3 7 2 9 1 5
- 4 8 6 7 2 9 1 5 3.
An implant comprising NDGA-polymerized collagen fibers having a tensile strength that is between about 180-350 MPa arranged as nine bundles, wherein each bundle is represented by a corresponding number 1, 2, 3, 4, 5, 6, 7, 8, and 9, respectively, and wherein the nine bundles have a repeating braid pattern defined by the following sequence:
- 2 3 4 5 6 1 8 9 7
- 3 4 2 6 1 8 9 7 5
- 4 2 6 1 8 3 7 5 9
- 2 6 4 8 3 7 5 9 1
- 6 4 8 3 7 2 9 1 5
- 4 8 6 7 2 9 1 5 3.
A bioprosthesis consisting essentially of NDGA polymerized collagen fibers, wherein the NDGA polymerized collagen fibers have a tensile strength that is between about 180-350 MPa and are arranged as about 10 to about 100 bundles of substantially parallel warp fibers and one or more weft fibers, wherein each bundle of warp fibers comprises at least two NDGA polymerized collagen fibers, and wherein the bundles of warp fibers and the one or more weft fibers are woven together to form a single-layer substantially planar construct.
A bioprosthesis comprising NDGA polymerized collagen fibers, wherein the NDGA polymerized collagen fibers have a tensile strength that is between about 180-350 MPa and are arranged as about 10 to about 100 bundles of substantially parallel warp fibers and one or more weft fibers, wherein each bundle of warp fibers comprises at least two NDGA polymerized collagen fibers, and wherein the bundles of warp fibers and the one or more weft fibers are woven together to form a single-layer substantially planar construct.
Dependencies are inferred from the claim text.