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US 8,168,433 B2Granted
Cell culture article and screening
AssigneeCorning Incorporated
InventorsJennifer Gehman, Arthur W. Martin, Zara Melkoumian, Christopher B. Shogbon, David M. Weber, Yue Zhou
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Abstract
A method for producing a cell culture article having a synthetic polymer layer for incubating with cells includes diluting one or more (meth)acrylate monomers in a solvent and dispersing the diluted monomers on a surface of the cell culture article. Some or substantially all of the solvent is removed and the monomers are then polymerized on the surface of the article to form the synthetic polymer layer attached to the surface of the article.
Claims19
A method for producing a cell culture article having a synthetic polymer layer, comprising:
- (a) diluting one or more (meth)acrylate monomers in a solvent;
- (b) dispersing the diluted monomers on a surface of a cell culture substrate;
- (c) removing about 80% or more of the solvent;
- and
- (d) polymerizing the monomers on the surface of the cell culture substrate after removing the about 80% or more of the solvent to form the synthetic polymer layer attached to the surface of the cell culture substrate.
2 more elements
Dependencies are inferred from the claim text.