Methods, systems and devices for reducing the size of an internal tissue opening

A system for treating a hole defined in a tissue structure between a left atrium and a right atrium of a heart, the hole defining an axis oriented axially through the hole, the system comprising:

• a handle body;
• a catheter coupled to said handle body;
• a tip portion extending from a distal end of said catheter;
• a tether system coupled to said handle body and extending through said catheter, said tether system including a first tether and a second tether, the first and second tethers each including a coil defining a lumen with a first wire and a second wire each extending through the lumen of the coil;
• and
• a medical device including a frame, said frame configured to assume a substantially flat configuration oriented substantially parallel to, or extending substantially along, the axis of the hole while in an intended, as-deployed state within the tissue structure, said frame including a central portion with at least a distal anchor and a first proximal anchor and a second proximal anchor extending from said central portion, each of said distal anchor, said first proximal anchor and said second proximal anchor configured to extend substantially coplanar with said central portion, said distal anchor configured to extend in the left atrium and said first and second proximal anchors configured to extend in the right atrium, said first proximal anchor configured to be directly coupled to said first tether and said second proximal anchor configured to be directly coupled to said second tether, said first and second proximal anchors configured to deflect proximally and continually extend substantially coplanar with said central portion as the tip portion moves distally over the first and second tethers toward the first and second proximal anchors;
• wherein the second wire includes a loop and the first wire is configured to engage with the loop of the second wire to couple the medical device and maintain the medical device taut against the coil.