Surgical stapling instruments including a cartridge having multiple staples sizes

A surgical stapling instrument comprising:

• an anvil having a plurality of staple forming depressions;
• a staple cartridge assembly having a tissue contacting surface defining staple retaining slots arranged for alignment with the staple forming depressions;
• a first plurality of staples and a second plurality of staples disposed in the staple retaining slots, each staple in the first plurality of staples having a first leg length and each staple in the second plurality of staples having a second leg length that is different from the first leg length;
• and
• a wound closure assembly having at supply line for delivering an amount of a wound closure material into the staple cartridge assembly.