US 8,148,558 B2Granted

Method of producing tibolone metabolites by fermentation with Fusarium lini

OwnerAttaur Rahman, Muhammed Iqbal Choudhary +2inventors

InventorsAttaur Rahman, Muhammed Iqbal Choudhary, Syed Adnan Ali Shah, Shamsun Nahar Khan

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Method of producing Δ4-Tibolone by contacting tibolone with Fusarium lini (ATCC 9593) is reported.

Dependent claims

A fermentation method of producing Δ4-Tibolone by contacting tibolone with Fusarium lini (ATCC 9593) in a culture media.

Dependencies are inferred from the claim text.

C07J 7/00
Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17
A61P 3/10
For glucose homeostasis: for hyperglycaemia, e.g. antidiabetics
C12N 9/99
Enzymes; Proenzymes; Compositions thereof ; Processes for preparing, activating, inhibiting, separating or purifying enzymes: enzyme inactivation…
C12P 33/00
Preparation of steroids

From the US filing history. Foreign family members aren’t listed.

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