Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field
AssigneeGiuliani International Limited
InventorsGiancarlo Naccari, Sergio Baroni
Life of this patent
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AssigneeGiuliani International Limited
InventorsGiancarlo Naccari, Sergio Baroni
Estimating the term…
Therefore the present invention relates specifically to the compounds of general formula (I), in which R1 and R2, which may be identical or different, are selected from the group comprising H, —CnH2n-1, a linear or branched alkyl group having from 1 to 6 carbon atoms, or together form an aromatic or aliphatic ring with 5 or 6 atoms; R3 is selected from —CO—CH3, —NHOH, —OH, —OR6 in which R6 is a linear or branched alkyl group having from 1 to 6 carbon atoms; R4 is selected from H, a linear or branched alkyl group having from 1 to 6 carbon atoms, phenyl, benzyl, —CF3 or —CF2CF3, vinyl or allyl; R5, R7, R8 are hydrogen atoms; or R3 and R4, R4 and R5, or R7 and R8 together form a ring, fused to the benzene, aromatic or aliphatic ring with 5 or 6 atoms comprising from 1 to 2 heteroatoms selected independently from the group comprising N, O. and use thereof in the medical field.
A compound of the general formula (I)
A compound selected from the group consisting of:
A compound the represented by the following structure:
A compound represented by the following structure
A compound represented by the following structure
A compound represented by the following structure
A compound represented by the following structure
A method of treating Crohn's disease, ulcerative rectocolitis or colon cancer in a human or animal in need thereof, comprising administering to the human or animal a compound selected from the group consisting of 4-amino-N-hydroxy-2-methoxybenzamide, 5-amino-N-hydroxy-2-methoxybenzamide, 5-amino-2,3-dihydrobenzofuran-7-carboxylic acid, 5-amino-2-ethoxy-N-hydroxybenzamide, 6-amino-2,2-dimethyl-4H-benzo[1,3]dioxin-4-one, and salts thereof.
A compound represented by (I):
Dependencies are inferred from the claim text.