Imprinted polymeric materials for binding various targets such as viruses
AssigneeUniversity of Maryland, College Park
InventorsPeter Kofinas, Daniel Janiak
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AssigneeUniversity of Maryland, College Park
InventorsPeter Kofinas, Daniel Janiak
Estimating the term…
Imprinted polymeric materials that selectively bind to a template article. Various types of template articles may be targeted by the imprinted polymeric materials, including microorganisms (e.g., viruses or bacteria) or biologic macromolecules (e.g., proteins or DNA). The imprinted polymeric material may be formed by template-directed synthesis using monomer units that interact with the template article. The monomer units are used to form a polymer matrix around the template article. Subsequently, the template article is removed from the polymer matrix. Also disclosed are imprinted polymeric materials comprising a cross-linked polymer matrix, which comprises a polyampholyte polymer. The polymer matrix has a binding cavity capable of selectively binding to a template article. Also disclosed are various uses for such imprinted polymeric materials.
An imprinted polymeric material comprising a cross-linked polymer matrix having a binding cavity capable of selectively binding a template article, wherein the polymer matrix comprises a polyampholyte polymer having monomer units at molar ratios that substantially complement the charge ratio of the template article.
A method of forming an imprinted polymeric material, comprising:
An imprinted polymeric material comprising a cross-linked polymer matrix having a binding cavity capable of selectively binding a template article, wherein the polymer matrix comprises a polyampholyte polymer having monomer units at molar ratios that substantially complement the charge ratio of the template article and wherein the polyampholyte polymer includes a monomer unit that is a weak acid.
Dependencies are inferred from the claim text.