Solvent-free moisture activated latent curing surgical adhesive or sealant

A liquid moisture activated solvent-free latent curing adhesive or sealant mixture comprising a poly(alkylene oxide)imine represented by formula I:

• wherein
• R1 is a linear or branched C1 to C14 residue optionally having one or more heteroatoms of a polyol that is selected from the group consisting of pentaerythritol, glycerol, tetra(2-hydroxypropyl)ethylenediamine and poly(alkylene oxide);
• R2 and R′2 are, independently of one another, a C1-C4 alkyl group;
• R3 and R′3 are, independently of one another, hydrogen or methyl group and different from one another, and for a liquid poly(alkylene oxide)imine sample, the average value for a1 is between 3 and 20, inclusive;
• and the average value for a2 is between 1 and 3, inclusive and the average value for f is between 2 and 6, inclusive;
• and
• an amine reactive moiety represented by Formula II:
• wherein R3 is a linear or branched C1 to C14 residue of a polyol, each R3 is bound to number of f3 reactive pendant chains and wherein the polyol is selected from the group consisting of pentaerythritol, glycerol, and poly(alkylene oxide), wherein the number of f3 reactive pendant chains is at least 2 but not greater than 6 and a3 is at least 3 but not greater than 10;
• and R3′ is a linear or branched C1-C4 alkylene group optionally having one or more oxygen atoms;
• and X is an isocyanate group,
• wherein the poly(alkylene oxide)imine and amine reactive moiety components are liquid under ambient conditions and present in the adhesive or sealant mixture in their neat forms.