Aldehyde conjugated flavonoid preparations
AssigneeAgency for Science, Technology and Research
InventorsJoo Eun Chung, Motoichi Kurisawa, Yi Yan Yang, Lang Zhuo
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Abstract
There is provided a method of conjugating a polymer containing a free aldehyde group with a flavonoid in the presence of an acid catalyst, such that the polymer is conjugated to the C6 or C8 position of the flavonoid A ring. The resulting conjugates may be used to form delivery vehicles to deliver high doses of flavonoids, and may also be used as delivery vehicles to deliver an additional bioactive agent.
Claims10
A method of conjugating a polymer having a free aldehyde group in the presence of acid to a flavonoid, comprising reacting the polymer with the flavonoid in the presence of an acid catalyst, the polymer being conjugated at the C6 and/or the C8 position of the A ring of the flavonoid.
Dependencies are inferred from the claim text.