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US 8,138,157 B2Granted
Antibiotic formulation and method of treatment
AssigneeFlow Pharma, Inc.
InventorReid M. Rubsamen
Life of this patent
Estimating the term…
Abstract
A formulation comprised of particles which may be in groups and are comprised of a biocompatible polymer and an antimicrobial drug for controlled release of the drug is disclosed. The particles may be in an aqueous solution comprising thrombin and be dispersed in a gel. The formulation is administered to an area such as an open wound having an orthopedic implant therein and provides a therapeutically effective level of drug to the patient over therapeutically effective period of time.
Claims16
A method of treating osteomyelitis, comprising:
- implanting an orthopedic implant into a surgical wound site;
- administering to the wound site a formulation comprised of a plurality of particles which particles are comprised of an antimicrobial drug and a biocompatible polymer;
- and
- allowing drug from the formulation to dissolve into the wound site over a period of time not less than one day and not more than seven days and provide a therapeutically effective dose of the drug over the period of time to thereby treat osteomyelitis.
1 more element
Dependencies are inferred from the claim text.