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US 8,138,156 B2Granted
Ophthalmic compositions containing diglycine
AssigneeBausch & Lomb Incorporated
InventorsSusan E. Burke, Erning Xia, Catherine Scheuer, Srini Venkastesh
Life of this patent
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Abstract
Ophthalmic composition comprising one or more polyglycines selected from the group consisting of diglycine, triglycine, tetraglycine and pentaglycine, or the salts of each thereof and one or more boron buffering compounds. The ophthalmic composition will have an osmolality of from 200 mOsmol/kg to 420 mOsmol/kg.
Claims11
An ophthalmic composition comprising diglycine, or a salt thereof,
- 10 ppm of α-[4-tris(2-hydroxyethyl)ammonium chloride-2-butenyl]poly[1-dimethylammonium chloride-2-butenyl]-ω-tris(2-hydroxyethyl)ammonium chloride, and
- boric acid and one or more borate salts, wherein the ophthalmic composition has an osmolality of from 200 mOsmol/kg to 420 mOsmol/kg.
An ophthalmic composition comprising:
- boric acid from 0.15% w/v to 0.6% w/v, sodium or potassium borate from 0.05% w/v to 0.5% w/v, and diglycine from 0.1% w/v to 0.7% w/v;
- 10 ppm of α-[4-tris(2-hydroxyethyl)ammonium chloride-2-butenyl]poly[1-dimethylammonium chloride-2-butenyl]-ω-tris(2-hydroxyethyl)ammonium chloride;
- and
- myristamidopropyl dimethylamine;
- wherein the ophthalmic composition has an osmolality of from 200 mOsmol/kg to 420 mOsmol/kg.
2 more elements
Dependencies are inferred from the claim text.