Back to results
US 8,137,967 B2Granted
In-vitro fertilization systems with spermatozoa separated into X-chromosome and Y-chromosome bearing populations
AssigneeXy, LLC
InventorsGeorge E. Seidel, Kehuan Lu, Tae Kwang Suh
Life of this patent
Estimating the term…
Abstract
An IVF system for successfully utilizing spermatozoa separated into X-chromosome bearing and into Y-chromosome bearing population for insemination. The IVF system includes fertilization medium that can shorten the time from insemination to cleavage and a portable incubator for the transportation of maturing oocytes and inseminated oocytes comprising a straw (19) and an incubation element (20) that can be sealed with a cap (22).
Claims12
A method of in vitro fertilization of oocytes, comprising the steps of:
- a) obtaining oocytes of a non-human mammal;
- b) obtaining sperm cells of said non-human mammal separated into an X-chromosome bearing population or a Y-chromosome bearing population;
- c) combining said oocytes of said non-human mammal in a fertilization medium supplemented with an amount of non-essential amino acids with said sperm cells of either said X-chromosome bearing population or said Y-chromosome bearing population;
- d) establishing said plurality of oocytes with said sperm cells of said X-chromosome bearing population or said Y-chromosome bearing population in incubation conditions within an incubation element;
- and
- e) fertilizing at least one of said oocytes of said non-human mammal with said sperm cells of said X-chromosome bearing population or said Y-chromosome bearing populations, said amount of non-essential amino acids sufficient to achieve an increased rate of development of the resulting at least one embryo.
3 more elements
Dependencies are inferred from the claim text.