Methods and compositions for tissue regeneration
AssigneeDFB Technology Holdings, LLC
InventorsEric Rolland, Thomas Hunziker, Beatrice Mis, Christopher Rinsch
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Abstract
A kit is disclosed that includes a first component comprising alginate, wherein the first component is comprised in a first sterile vial, and a second component comprising cells comprising keratinocytes or fibroblasts, or mixtures thereof, that secrete one or more biologically active molecules selected from the group consisting of GM-CSF, VEGF, KGF, bFGF, TGFβ, angiopoietin, EGF, IL-Iβ, IL-6, IL-8, TGFα, and TNFα, wherein the cells are allogeneic and mitotically inactive, a buffered solution, and human serum albumin or a cryoprotectant, wherein the second component is comprised in a second sterile vial.
Claims14
A kit comprising:
- (a) a first component comprising alginate, wherein the first component is comprised in a first sterile vial;
- and
- (b) a second component comprising:
- cells comprising keratinocytes or fibroblasts, or mixtures thereof, that secrete one or more biologically active molecules selected from the group consisting of GM-CSF, VEGF, KGF, bFGF, TGFβ, angiopoietin, EGF, IL-Iβ, IL-6, IL-8, TGFα, and TNFα, wherein the cells are allogeneic and mitotically inactive;
- a buffered solution;
- and
- human serum albumin or a cryoprotectant,
- wherein the second component is comprised in a second sterile vial.
Dependencies are inferred from the claim text.