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US 8,137,950 B2Granted
Bacteriophage resistant lactic acid bacteria
AssigneeChr. Hansen A/S
InventorsBirgitte Stuer-Lauridsen, Thomas Janzen
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Abstract
A lactic acid bacterium (LAB) wherein an YjaE protein is essentially inactive and the LAB thereby get improved resistance to bacteriophages, a starter culture composition comprising the lactic acid bacterium and use of this starter culture manufacturing a food or feed product.
Claims20
A lactic acid bacterium wherein an YjaE protein, expressed by an yjaE gene, is inactive, wherein said inactive YjaE protein is functionally inactive with respect to phage infection, and wherein the YjaE protein is expressed by a yjaE gene comprising a DNA sequence selected from the group consisting of:
- (a) the DNA sequence of SEQ ID NO 1 (IL1403 yjaE DNA coding sequence);
- and
- (b) a DNA sequence that encodes a polypeptide, having YjaE protein activity, that is at least 70% identical to the polypeptide sequence of SEQ ID NO 2 (IL1403 YjaE protein sequence);
- and wherein the YjaE protein is inactive due to a modification introduced into the yjaE gene.
1 more element
Dependencies are inferred from the claim text.