Drug delivery nanocarriers targeted by landscape phage

A targeted drug delivery nanocarrier, the nanocarrier comprising:

• a plurality of phospholipid molecules;
• a targeting landscape phage protein assembly that is denatured and has a spheroid conformation;
• and a plurality of drug molecules;
• wherein the phospholipid molecules form a liposome comprising a phospholipid bilayer having the drug molecules contained therein and the targeting landscape phage protein assembly is complexed to the liposome via self-assembly and proteins of the targeting landscape phage protein assembly are oriented with their N-terminus on the surface of the liposome and their C-terminus in the interior of the liposome and wherein the targeting landscape phage protein assembly displays a binding peptide on the surface of the liposome that is selected to specifically and selectively bind to a target site, and wherein the landscape phage protein assembly is a filamentous bacteriophage coat protein assembly that displays the binding peptide in a pVIII major coat protein.