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US 8,137,560 B2Granted
Separation process
AssigneeGe Healthcare Limited
InventorMette Husbyn
Life of this patent
Estimating the term…
Abstract
The present invention relates to a process for separating a target radiolabelled compound from an impurity, apparatus for performing such a process and a removable cassette for use in such apparatus. Also provided are methods for using the target radiolabelled compound obtained by a method comprising the separating process of the invention.
Claims8
A process for separating a target radiolabelled compound and one or more impurities, wherein the target radiolabelled compound is a radiolabelled thymidine or thymidine derivative, the process comprising,
- providing a mixture comprising the target radiolabelled compound and one or more impurities;
- passing the mixture through a solid phase extraction column to adsorb the target radiolabelled compound and adsorb said one or more impurities, said solid phase extraction column containing poly(styrene divinyl benzene) surface modified with 2-piperidone;
- eluting said one or more impurities using a first elution solution;
- and,
- eluting the target radiolabelled compound using a second elution solution.
2 more elements
Dependencies are inferred from the claim text.